Growth hormone deficiency occurs when the body does not produce the required amount of growth hormones. These protein-based hormones are secreted by the pituitary gland. These vital hormones are necessary for cell regeneration, reproduction, and growth.
Growth hormone deficiency can occur at any age, although the symptoms differ at different stages. In children, it is needed for normal growth. In adults, it maintains the balance between fat, bone, and muscles. Adults can also show emotional effects when suffering from GH deficiency.
In children, GH deficiency manifests itself as abnormally short height. It may be present at the time of birth. It can also develop later as a result of a brain tumor or injury or any particular medical condition.
Children suffering from growth hormone deficiency are typically shorter than other children of their age. Their rate of growth is slow, less than 2 inches an year. However, they have normal body proportions and intelligence. Puberty comes late, or not at all.
The effect of growth hormone deficiency among adults is different. Here the concern is not so much the short stature, but the changes that it can bring upon. These are changes in the body composition and the psychological health of the patient. Changes in body composition reflect in the change of fat to muscle ratio and changes in lipid profile.
While there is a decrease in muscle, fat accumulates in the body. There is an increase in ‘bad’ LDL cholesterol, while the good ‘HDL’ cholesterol decreases. There are some visible symptoms that signify psychological changes. There is a visible loss of energy. In addition, there is a preference for isolation, a lack of interest in surroundings and even depression.
Fortunately, today growth hormone can be synthetically produced in a laboratory using recombinant DNA technology, also known as human growth hormone or HGH. In case of GH deficiency, a physician will be prescribed the dosage after checking GH levels in the body.
Although the mode of treatment may be the same, the objective may differ for children and adults. In children, it is necessary for normal linear growth and restoring the body composition. In adults, it looks to improve body composition, strength, and improving the quality of life.
GH are key hormones, necessary for the growth and development of all cells. Growth hormone deficiency can severely affect children and adults. With the right dose of HGH, this deficiency in our body can be fulfilled.